Which factor significantly affects the likelihood of success in regenerative surgery?

The depth and width of bone defects play a critical role in determining the success of regenerative surgery. In periodontal regeneration, the size and characteristics of the bone defect directly influence the healing potential and the ability of the regenerative material to integrate with the surrounding tissues.

More complex or larger defects may present greater challenges for regeneration due to the difficulty in effectively delivering regenerative materials or achieving proper blood supply and oxygenation in these areas. Shallow or narrow defects may allow for easier access and a more straightforward healing process, facilitating a higher rate of success in regenerating healthy periodontal tissues, including bone and connective tissue.

In contrast, while factors like the patient's age, the presence of systemic disease, and the amount of plaque can also influence surgical outcomes, they do not impact the surgical regenerative process to the same extent as the physical characteristics of the bone defect itself. Therefore, the depth and width of the defect are paramount in evaluating the expected success rate of regenerative surgical procedures.